The parasite Toxoplasma gondii has some favorable effects on the pathogenesis and progression of a mouse model of Alzheimer's disease, reports a study in the open access journal PLoS ONE.
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Toxoplasma gondii, a parasite commonly hosted in cats and
generally known for the potential complications it can cause for human
pregnancies, suppressed the immune system.
The researchers behind this study, led by Eun-Hee Shin of the Seoul
National University College of Medicine, found that this immune system
suppression had positive effects on Alzheimer's disease mouse models,
resulting in a significant decrease in the amount of b-amyloid plaque
deposition, a hallmark of Alzheimer's disease, and better performance in
behavior tests like a water maze.
